Horton Hears a Who!

Horton the elephant struggles to protect the unseen, infinitesimal creatures of who-ville, who live on a speck of dust, but he meets with the derision of other animals who think he's gone mad and threaten to destroy the speck of dust; However, Horton persuades the tiny creatures to save themselves by making as much noise as possible so that they can be heard and thereby prove their existence to the other animals. (20th Century Fox AU)